Potassium citrate is a combination of potassium salt and citric acidity.
While it’s frequently utilized as a food additive, it may also improve heart and bone health insurance and help conditions like kidney gemstones.
This short article examines potassium citrate and when and how to make use of the product securely.
What’s Potassium Citrate?
Potassium is a vital mineral present in various fiber-wealthy foods like vegetables, fruits, nuts and legumes.
Should you consume a largely plant-based diet, there’s a high probability you’re getting enough potassium. If your diet includes more junk foods, you might not be consuming an sufficient amount.
Unlike other important nourishment (like calcium, vitamin D and B-vitamins), potassium isn’t prepared (added) in staple foods. It’s because its rapid effect on bloodstream pressure.
However, when potassium is consumed from natural sources such as these, the associated fiber slows its absorption. This enables it to securely perform its role in your body.
In supplemental or medication form, potassium is coupled with other molecules like carbonate, chloride or hydroxide to create salts.
Potassium associated with citric acidity forms potassium citrate.
Potassium citrate structure. Image source.
Roles of Potassium
It serves many purposes in your body, however it mostly functions being an electrolyte that can help control muscle and nerve function.
Potassium can also be fundamental to heart health, urinary function, acidity-base balance, gastrointestinal motility as well as other enzyme reactions.
Due to these roles, you can use it to aid a number of health problems.
Potassium citrate particularly produces alkalizing effects in your body, assisting to balance urinary pH levels.
Summary: Potassium is a vital mineral present in many fiber-wealthy whole-foods. It’s essential for various functions in your body like electrolyte and acidity-base balance. Potassium citrate is really a salt that can help regulate urinary pH levels.
Possible Health Advantages of Potassium Citrate
Potassium citrate provides a couple of notable health advantages, specifically for the kidneys.
Potassium Citrate and Kidney Gemstones
Potassium citrate is most frequently accustomed to improve kidney gemstones.
Citrate particularly helps you to remove protons, or positively billed atoms, which reduces acidity within the urine.
Furthermore, potassium citrate crystallizes stone-developing salts like calcium oxalate, calcium phosphate and the crystals within the bladder.
Crystallization is really because of two mechanisms of potassium citrate. Zinc heightens urine pH, which makes it more alkaline. Additionally, it increases urine citrate levels, which lowers the chance of stone formation.
Research has shown that using potassium citrate decreases stone formation and recurrence.
Basically, it protects against elevated urine saturation caused by high-protein diets.
Citrate within the urine has the capacity to bind to calcium, which makes it more soluble and fewer in a position to create calcium oxalate gemstones (1, 2, 3, 4, 5).
Overall, maintaining acidity-base balance within the bladder is essential for stopping all kinds of kidney gemstones (6).
A current Cochrane review discovered that potassium citrate might help reduce recurrent calcium urinary gemstones in youngsters. However, many children couldn’t handle the therapy because of adverse negative effects. The authors had limited confidence within this finding and expressed the requirement for more evidence (7).
Research on 57 adults with active kidney gemstones demonstrated that potassium citrate therapy helped to improve urine pH, citrate and potassium levels when compared with placebo. The research figured that potassium citrate helped reduce stone formation with simply two subjects experiencing mild negative effects (2).
Potassium Citrate and Strokes
Potassium’s impact on bloodstream pressure and heartbeat might help prevent stroke.
A 12-year prospective study demonstrated that each 390mg rise in nutritional potassium brought to some 40% decrease in stroke-connected dying (8).
Also, a meta-analysis on potassium and cardiovascular risks reviewed 22 studies. It discovered that potassium intake reduced bloodstream pressure in individuals with hypertension and helped lower the chance of stroke (9).
The Food and drug administration is presently collecting data on potassium citrate use and stroke risk.
To date, from the 1,749 individuals who experienced negative effects during potassium citrate, 15 or .86% have experienced a stroke, particularly in older males (10).
Potassium Citrate and Bone Health
There’s mixed evidence on whether potassium citrate is advantageous to bone health.
Once the is too acidic (frequently the situation when eating the conventional American Diet), calcium is pulled in the bones to assist alkalinize the bloodstream.
Therefore, it’s vital that you maintain proper pH balance for bone health, even when your calcium intake is sufficient (11).
In a single study, 52 adults supplemented with , 2345 or 3519 mg/day’s potassium citrate for six several weeks. They discovered that 3519mg/day helped improve calcium balance, that could theoretically safeguard the bones (12).
Another study saw significant increases in bone mineral density (BMD) in healthy seniors men and women without brittle bones who required 2345mg of potassium citrate for twenty-four several weeks. Additionally they received calcium and vitamin D supplements, who have performed a job too (13).
In healthy, postmenopausal women, however, using supplemental potassium citrate over 2 yrs didn’t reduce bone turnover or increase BMD (14).
These results contrast using the evidence present in a laboratory study, which demonstrated that potassium citrate could prevent osteopenia (low BMD) progression (14, 15).
Summary: Potassium citrate might help prevent kidney stone formation, and can also prevent a stroke. There’s also conflicting evidence on whether or not this can improve bone health. Overall, it’s safest to eat potassium from food sources.
Potassium Citrate Recommendations
The product ought to be used under medical supervision.
Prescription potassium citrate is frequently offered underneath the trade name Urocit-K, although generic forms can be found.
It is also purchased like a dietary supplement by itself or inside a multivitamin/mineral formulation.
Here is a listing of ideas to follow when utilizing potassium citrate:
- Always go with food
- Space it into multiple doses during the day
- Go with a minimum of 8 oz. water
- Don’t crush or split the tablets
- Don’t use along with salt substitutes, which frequently contain potassium
- Don’t improve your dose without talking to your physician
Dosage amounts will be different by person.
Generally, healthy adults require 4.7 grams of potassium each day.
With hypokalemia (low potassium levels), dosing increases to deal with and stop the deficiency. Serum potassium levels should stay between 3.5 and 5 mEq/L.
Dosing may also be monitored according to urinary citrate levels, which needs to be between 320-640mg/day.
You shouldn’t exceed 7,819mg each day or serious health effects may end up.
Summary: Just use potassium citrate as suggested by your personal doctor. They’ll help find the proper dose that you should keep serum potassium and urinary citrate levels in balance.
Negative Effects of Potassium Citrate
Many negative effects can be cultivated while using the potassium citrate.
Bloodstream and urine testing, in addition to electrocardiographs (ECG), can assess your wellbeing status while using the potassium citrate.
Large doses within the suggested amount could cause cardiac arrhythmia.
Other part effects include:
- Allergy symptoms
- Bloody or black stools
- Confusion, dizziness
- Irregular heartbeat, chest discomfort, elevated bloodstream pressure
- Muscle twitching
- Trouble sleeping, irritability
- Numbness in hands/ft
- Stomach discomfort
- Painful swallowing
- Unusual bleeding/bruising
- Unusual weakness
Report these negative effects for your physician.
Who Should Avoid Potassium Citrate
Individuals using the following health conditions should avoid potassium citrate:
- Severe kidney disease
- Heart damage
- Addison’s disease
- High amounts of potassium or sodium within the bloodstream
- Severe lack of fluids
Consult with your physician the security and suitability of utilizing potassium citrate using the following conditions:
- Cardiovascular disease
- Low bloodstream calcium levels
- Kidney disease
- Stomach ulcers
- Swallowing difficulty
- Urinary system infections
- Chronic diarrhea
- Pregnant or looking to get pregnant
- Allergy to potassium citrate or any other preservatives
If you work with certain medications or supplements, enable your physician know just before beginning a potassium citrate regimen.
Many generally used products communicate with potassium citrate including NSAIDS, antacids, cold/allergy medications, aspirin and diuretics.
Also, many dietary supplements like multivitamins and mineral formulas contain potassium. Make sure to report their use for your physician to prevent overdosing.
Summary: High-risk negative effects can happen when utilizing potassium citrate, so it’s vital that you be carefully monitored with a medical expert. Report all medications and supplements you’re taking to prevent interactions or overdosing. Individuals with certain severe health conditions impacting the center, adrenals or kidneys must avoid using potassium citrate.
Potassium Citrate for Dogs
Dog proprietors could use potassium citrate to assist their pup with urinary gemstones or painful or frequent peeing.
One study given 12 healthy dogs whether standard diet a treadmill with 150mg potassium citrate per kilogram of bodyweight, two times each day.
The authors discovered that supplementation were built with a limited effect, having a slight rise in urine pH of .2 units. In either case, if you opt to supplement, they recommend you need to do so with food, two times each day (16).
Overall, the study is sparse about this subject despite various pet-friendly potassium citrate products in the marketplace. Engage with your vet if you are thinking about using potassium citrate for the pet.
Summary: Potassium citrate may be used to help dogs with urinary issues, though there’s limited research to demonstrate this. Engage with your vet for safety and dosing recommendations.
If You Work With Potassium Citrate?
Potassium citrate might help people, and often dogs, with treating kidney gemstones.
It assists to prevent stroke, but can be used carefully and underneath the supervision of your personal doctor.
Evidence because of its effects on bone health are inconclusive, so it’s better to be cautious and acquire sufficient potassium intake from food sources.
Dosing is dependant on individual have to maintain healthy serum potassium levels.
Several serious negative effects migh result if used incorrectly. Should you suffer heart, kidney or adrenal disease, ask your physician if potassium citrate is suitable for you personally.